International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)

Abstract

A STUDY ON CHANGES IN SERUM GGT AND MAGNESIUM LEVEL IN ALCOHOLIC LIVER DISEASE

Author(s): Gandhi Paulin A, Sendhav Sandip S, Sanghani Hiren I, Patel Arpita P

Aims: A study on changes in Serum GGT and Magnesium level in Alcoholic Liver Disease. Material and Methods: Serum GGT and Serum Mg++ were estimated with the help of commercially available kit in patients of Alcoholic Liver Disease (n=50) and Normal Individuals (n=50) on fully automated biochemistry analyzer Erba XL-640. Results: Serum GGT level was found significantly higher (P< 0.01) in Alcoholic patients as compared to healthy non-alcoholics. Moreover Serum Mg++ was found significantly lower (P< 0.01) in Alcoholic Liver Disease as compare to normal Individuals. In addition to that there is significant inverse correlation (r= - 0.553) between serum GGT and Mg++ in study group. Conclusions: None of the individual tests of conventional liver function tests are of much importance in diagnosis of liver disease; however when many of the liver function tests are abnormal at the same time, liver disease is the most probable diagnosis. Data of the present study clearly conclude that serum GGT activity along with serum Mg++ status can be useful marker for alcoholic liver disease.


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