Research
Sgot and Sgpt Variations with their Pearson?s Coefficient Correlation in Sickle Cell Disease
Author(s): Chandrakant G. Kamble, Prashant J. Hisalkar, Ivvala Anand Shaker and Jagdish Powar
Background: Sickle cell disease is an inherited disorder caused by the single point mutation due to the replacement of valine for glutamic acid at the sixth codon of β-chain of globin’s (β6Glu-Val). The sickle cell disease condition with hepatic dysfunction shows abnormal variations in liver function tests including serum aminotransferases enzymes like Serum Glutamic-Oxaloacetic Transaminase (SGOT) and Serum Glutamic Pyruvic Transaminase (SGPT) levels were changed to discuss their significance in sickle cell disease. Objectives: Study of SGOT and SGPT level variation in sickle cell disease. Study of Pearson’s correlation coefficient of Serum Glutamic-Oxaloacetic Transaminase (SGOT) and Serum Glutamic Pyruvic Transaminase (SGPT) in sickle cell disease. Methods: This study was conducted in the Department of Biochemistry, People’s College of Medical Sciences a.. Read More»
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