Research
Assessment of Outcome and Feasibility of Bladder Preservation Therapy in Muscle Invasive Bladder Carcinoma: A Prospective Observational Study with Meta-analysis
Author(s): Mukteshwar Kumar, Arpan Yadav, Kanishka Kumar and Ishwar Ram Dhayal
Background: Radical Cystectomy (RC) is the standard of care for the management of Muscle Invasive Bladder Cancer (MIBC). Considering perioperative complications coupled with a classically older patient population with multiple comorbidities has led patients and clinicians to seek alternatives to cystectomy like organ-preserving therapies in the management of bladder cancer over the past several decades. Objectives: The primary objectives were to assess the outcome (overall survival, recurrence-free survival) of bladder preservation therapy in patients with muscle invasive bladder carcinoma and to compare the outcome of bladder preservation therapy with the outcome of radical cystectomy in patients with muscle invasive bladder carcinoma. Methods: In a prospective observational setting patients with clinical stage T2-T4aN0M0 (after initial cystoscopic biopsy) carcinoma of the urinary bl.. Read More»
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