International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)
Saurabh Sabnis
Rural Dental College, Pravara Institute of Medical Science, Maharashtra, IndiaPublications
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Review
Regeneration of Biomimetic Hydroxyapatite on Acid Etched Human Enamel using PAMAM Template in Vitro
Author(s): Rahul Pandhare*, Saurabh Sabnis, Rahul Kunkulol, Deepak Vikhe, Gajanan Pandhare and Lehya Mounica Kadali
Introduction: Traditional dental restorative materials do not fit well with the natural tissue at the lesion interface because their components, structure, and properties are not similar to those of the natural hydroxyapatite. Objective: To mimic the natural biomineralization process regulated by amelogenin in developing enamel using a PAMAM template. This work will explain the nature of PAMAM-PO3H2 with acid-etched enamel in a mineralization solution. Methodology: Here, we attempted to use a phosphate-terminated PAMAM dendrimer and investigate its application as an amelogenin analog on the remineralization process of acid-etched enamel. The fourth generation PAMAM-PO3H2 was arranged. For the mineralization solution, a 3 ml calcification solution containing 2.58 mM CaCl2 and 1.55 .. Read More»
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