GET THE APP

A 1-Year Randomized Controlled Trial of Topical Sucralfate vs. Silver Sulfadiazine in the Management of Second-Degree Burns | Abstract
Logo

International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)

Abstract

A 1-Year Randomized Controlled Trial of Topical Sucralfate vs. Silver Sulfadiazine in the Management of Second-Degree Burns

Author(s):Devendra Dhaker and Arvind Joshi*

Background: Small scars have been linked to bad psychosocial outcomes emphasizing the necessity of wound healing treatments that are successful. According to burn clinicians, there is a strong link between scar formation and the time it takes to re-epithelialize, especially in children. The major goal of burn wound healing is to speed up the healing and closure process. Aim: The current research aimed to examine the effects of Silver sulfadiazine, and topical Sucralfate in the treatment of second-degree superficial burn wound healing. Methods: The study enrolled 80 patients of both sex under the age group of 30 years with 50 percent second-degree superficial burns. Patients were evenly split into two groups. Patients in group A received topical sucralfate dressing, whereas those in group B received 1% Silver sulfadiazine dressing. The patients’ demographics, history, physical, and systemic examinations were all documented and for the detailed analysis, SPSS 20.0 was employed. Results: Granulation emerged in 20 (50%) of patients in less than a week, while in group B, granulation appeared between 15 and 20 days in 22 (55%) of patients (p=0.134). The average day of granulation in group A was 8.12 ± 1.96 days compared to 8.94 ± 3.69 days in group B (p=0.392). On days 1, 7, and 14, the wound culture was performed. Conclusion: Topical sucralfate dressing is more effective than silver sulfadiazine dressing in terms of promoting early granulation in the healing of second-degree superficial burns, but its antibacterial activity is equivalent to silver sulfadiazine dressing. To reinforce the notion, multicentric experiments with larger sample sizes are required.


Select your language of interest to view the total content in your interested language

Archive
Scope Categories
  • Clinical Research
  • Epidemiology
  • Oncology
  • Biomedicine
  • Dentistry
  • Medical Education
  • Physiotherapy
  • Pulmonology
  • Nephrology
  • Gynaecology
  • Dermatology
  • Dermatoepidemiology
  • Otorhinolaryngology
  • Ophthalmology
  • Sexology
  • Osteology
  • Kinesiology
  • Neuroscience
  • Haematology
  • Psychology
  • Paediatrics
  • Angiology/Vascular Medicine
  • Critical care Medicine
  • Cardiology
  • Endocrinology
  • Gastroenterology
  • Infectious Diseases and Vaccinology
  • Hepatology
  • Geriatric Medicine
  • Bariatrics
  • Pharmacy and Nursing
  • Pharmacognosy and Phytochemistry
  • Radiobiology
  • Pharmacology
  • Toxicology
  • Clinical immunology
  • Clinical and Hospital Pharmacy
  • Cell Biology
  • Genomics and Proteomics
  • Pharmacogenomics
  • Bioinformatics and Biotechnology
  • Recommended Conferences