Objective: To assess serum phosphate and magnesium level in type-2 diabetic patients in comparison with those of control subjects. Methodology: There were 100 diabetic patients and 100 age matched non-diabetic (control) subjects included in this study. Serum phosphate, serum magnesium and fasting and postprandial blood sugar measured among the diabetic and control groups using SPSS version 16.0 for analysis. Results: Serum phosphate level was significantly lower in diabetic patients (2.92 ± 0.75) as compared to control subjects (3.38 ± 0.49). Serum magnesium levels were significantly lower in diabetic patients (0.9 ± 0.15) compared to controls (2.75 ± 0.46) Conclusion: The study reveals that hyperglycemia may reduce serum levels of magnesium and phosphorus.