Logo

International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)

www.hxznw.com www.micaze.com www.bursaglobe.com www.enjoyantalya.com www.gzzzn.com pornofb.com pornstab.com xvideosxporn.com burdur escort bartın escort eskişehir escort izmir escort escort bursa üvey anne pornosu escort izmir
Abstract

Air Way Bacterial Colonization in COPD Patients at Stable and the Exacerbated States

Author(s): Wedad M. Abdelraheem, Ebtisam S. Mohamed, Elham A. Abdelghany, Rasha M. Emam and Manar S. Mohamed

Objectives: The aim of this study was to investigate the prevalence and load of airway bacteria in chronic obstructive pulmonary disease (COPD) patients and to detect the antibiotic susceptibility pattern of the isolated strains. Methods: The current study included 50 COPD patients. Paired sputum samples were taken from all patients, one at the exacerbation state and the other at the stable state. Identification of bacterial species was done using standard microbiological techniques and PCR. Results: There were 41 samples out of 50 (82%) positive for bacteria at exacerbation compared with 12 samples out of 50 (24%) positive for bacteria (either by culture or PCR or both) at stable state samples (p=0.001). The most commonly detected species was H. influenza and S. pneumoniae. There were a total of 27 bacterial species detected by PCR not detected by culture and only 4 bacterial species detected by culture not detected by PCR (p=0.001). Isolated strains show a high resistance pattern to the tested antibiotics and multi drug resistant strains were detected. Conclusions: This study has shown that airway bacterial prevalence and load increase at COPD exacerbations, and there is a significant relationship between lower airway bacterial colonization and COPD.


Card image
Subscribe Now!
Scope Categories
  • Clinical Research
  • Epidemiology
  • Oncology
  • Biomedicine
  • Dentistry
  • Medical Education
  • Physiotherapy
  • Pulmonology
  • Nephrology
  • Gynaecology
  • Dermatology
  • Dermatoepidemiology
  • Otorhinolaryngology
  • Ophthalmology
  • Sexology
  • Osteology
  • Kinesiology
  • Neuroscience
  • Haematology
  • Psychology
  • Paediatrics
  • Angiology/Vascular Medicine
  • Critical care Medicine
  • Cardiology
  • Endocrinology
  • Gastroenterology
  • Infectious Diseases and Vaccinology
  • Hepatology
  • Geriatric Medicine
  • Bariatrics
  • Pharmacy and Nursing
  • Pharmacognosy and Phytochemistry
  • Radiobiology
  • Pharmacology
  • Toxicology
  • Clinical immunology
  • Clinical and Hospital Pharmacy
  • Cell Biology
  • Genomics and Proteomics
  • Pharmacogenomics
  • Bioinformatics and Biotechnology
    International Journal of Medical Research & Health Sciences © 2012-2019 [Last updated: March 20, 2019]