Antioxidant Action of Green Tea Extract in Alloxan-Induced Diabetic Albino Rats: An Experimental Laboratory-Based Study | Abstract

International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)


Antioxidant Action of Green Tea Extract in Alloxan-Induced Diabetic Albino Rats: An Experimental Laboratory-Based Study

Author(s):Ali Hassan A. Ali*, Ali Yaqoub Alali, Rasheed A. Alhajri, Abdulrahman M. Aldawsari, Ammar H. AlHeseni and Nasser S. Aldosari

Background: Green tea extract can regulate blood sugar and encourage weight loss due to its high antioxidant content. Several studies have shown that green tea extract can improve general health and may help protect against many diseases. Most patients with diabetes are associated with poor fertility. Aim of the work: The present study aimed to evaluate the importance of green tea extract supplementation in reducing metabolic abnormalities associated with alloxan-induced diabetes in male albino rats. Material and Methods: This study was conducted on thirty male albino rats with an average weight of 100 grams-110 grams. The rats were divided equally into three groups that included control, diabetic and diabetic took green tea extracts orally (50 mg/Kg/day) for three weeks. A single dose of alloxan (120 mg/kg body weight) was used to induce diabetes in rats. Diabetic rats were given 50 mg/kg body weight green tea extracts orally for thirty days twice per day. The morphological and histological structures of the testis were compared in different groups of rats. Results: It was revealed that the morphological testicular changes observed in diabetic groups were significantly improved after treatment with green tea compared to the control group. Conclusion: These results prove that green tea improves oxidative damage caused by diabetes in the testis of male rats.

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