Background: Significant difference exists between clinical and ultra-sonographic liver span in the MCL in the subjects. Aim: To measure liver span in normal healthy adults clinically and by using ultrasonography. Materials and Methods: The study was conducted on 100 healthy subjects aged 18-65 years. Liver span was calculated by clinical examination followed by USG evaluation. Results: The mean clinical liver span measured in mid-clavicular line in males was 11.99 cm ± 1.6 cm and in females it was 11.05 cm ± 1.5 cm. Ultra-sonographic mean liver span in males was 14.16 cm ± 1.32 cm while in females it was 12.79 cm ± 1.40 cm. Conclusion: Significant difference was found between clinical and ultra-sonographic liver span in the MCL in the subjects (p<0.001).