Introduction: Bioethics has gained lots of importance in the present days and especially very important in the field of medical research. Doctors, medical students, nursing staff and other paramedical staff are directly or indirectly involved in the clinical and research activities. A proper training in bioethics is very essential especially for medical students nursing and other paramedical staff. There are various teaching methodologies like a black board (lecturing), power point presentations, case discussions, group discussions and film/movie clipping related to bioethics .Each of the teaching methodology is effective in a particular group. Materials and methods: Four different teaching methodologies were used to teach bioethics in four different categories namely MBBS students, doctors/interns, nurses and lab technicians. All were exposed to all types of teaching methodology. An evaluation was done by performance based and choice based evaluation system. Results: Case discussion was most popular choice of MBBS students and Doctors/Interns. Among nurses and lab technician’s film discussion was best in terms of performance and choice. Conclusion: Bioethics covers more about abstract issues related to the health discussion on this topic help in better understanding and clarification.