Background: The prevalence of depression in diabetes mellitus is 46.15%. There is an association of mood, glycemic control, and cognition and behavior problems in Type II DM which disturbs the HPA-axis and increases the production of cortisol leading to an increase in insulin resistance. Thus, we aimed to analyze the correlation between the duration of type 2 DM and Depression. Methods: A total of 60 participants were recruited in this cross-sectional correlation study. The patients were between 20-40 years of age with 5, 10, and 15 years of type 2 diabetes mellitus who are on medications. The individuals who are diagnosed with type 1 DM, uncontrolled type 2 diabetes mellitus, cancer, or any neurological conditions were excluded. The correlation between the duration of type 2 DM and Depression was assessed using Problem Areas In Diabetes scale (PAID). Results: The Chi-square test showed a higher depression level in Group C than A and lowest in Group B. There was no significant correlation seen in Depression with age and BMI. But there was a significant correlation seen between the Duration of type 2 DM and Depression (p-value=0.0137*). It indicates a strong positive correlation between Depression and Duration of type 2 DM. Conclusion: The study demonstrated there was a significant correlation between Depression and Duration of type 2 DM.