International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)

www.hxznw.com www.micaze.com www.bursaglobe.com www.enjoyantalya.com www.gzzzn.com pornofb.com pornstab.com xvideosxporn.com burdur escort bartın escort eskişehir escort izmir escort escort bursa üvey anne pornosu escort izmir

Correlation of Osteocalcin Level with Blood Glucose Concentration and Insulin Level in Type II Diabetic Sudanese Patients

Author(s):Ogail Yousif Dawod, Amar Babikir Elhussein, Mohamed Abd El-Rahim Ahmed, Nour Eldaim Elnoman Elbadawi and Omer Abdel Aziz Musa

Osteocalcin, a bone-derived protein, has recently been reported to affect energy metabolism, this study aimed to evaluate the effects of osteocalcin level on blood glucose concentration and insulin level in type II diabetic Sudanese patients. In this cross-sectional study, one hundred fifteen type II diabetic patients were enrolled in the study (34 males and 81 females) with ages ranging between 18 and 90 years. Total osteocalcin, undercarboxylated osteocalcin, and insulin were measured using ELISA technique. Fasting blood glucose and lipid profile were measured by a spectrophotometer. Mean serum osteocalcin concentration in diabetic patients was significantly lower than those in control subjects (p ≤ 0.001). Undercarboxylated osteocalcin in diabetic patients was significantly lower than in control subjects (p ≤ 0.001). Fasting insulin was significantly higher in diabetic subjects compared to control subjects (p ≤ 0.001). Osteocalcin was negatively correlated with insulin and FBS (r = −0.530; p ≤ 0.001), (r = −0.373; p ≤ 0.001) respectively. Undercarboxylated was negatively correlated with insulin and FBS (r = −0.634; p ≤ 0.001), (r = −0.297; p ≤ 0.001) respectively. Total osteocalcin and undercarboxylated osteocalcin levels of diabetic patients were lower than those of the healthy control subjects. Fasting serum insulin was higher in patients compared to control subjects. Total osteocalcin and undercarboxylated osteocalcin were negatively correlated with Fasting serum insulin and FBS.

Card image
Subscribe Now!
Scope Categories
  • Clinical Research
  • Epidemiology
  • Oncology
  • Biomedicine
  • Dentistry
  • Medical Education
  • Physiotherapy
  • Pulmonology
  • Nephrology
  • Gynaecology
  • Dermatology
  • Dermatoepidemiology
  • Otorhinolaryngology
  • Ophthalmology
  • Sexology
  • Osteology
  • Kinesiology
  • Neuroscience
  • Haematology
  • Psychology
  • Paediatrics
  • Angiology/Vascular Medicine
  • Critical care Medicine
  • Cardiology
  • Endocrinology
  • Gastroenterology
  • Infectious Diseases and Vaccinology
  • Hepatology
  • Geriatric Medicine
  • Bariatrics
  • Pharmacy and Nursing
  • Pharmacognosy and Phytochemistry
  • Radiobiology
  • Pharmacology
  • Toxicology
  • Clinical immunology
  • Clinical and Hospital Pharmacy
  • Cell Biology
  • Genomics and Proteomics
  • Pharmacogenomics
  • Bioinformatics and Biotechnology
  • Recommended Conferences

    International Conference on Haematology and Medical Oncology

    Edinburgh, Scotland

    Medical Summit and Expo on Healthcare and Medicine

    London, United Kingdom