Aim: To investigate the differences in SBS of orthodontic brackets after applying a caries resin infiltrant and its relationship to the bond type used. Materials and methods: A total of 48 extracted upper premolar were divided to four groups, and the force required for debonding of brackets was recorded. Residual adhesive material was examined by light microscopy. Statistical analysis was performed included t-test and Chi-square test. Result: The highest bond strength (22.543 MPa) was get by use the caries infiltrant with self-etching bond. More residual adhesive was observed on infiltrated enamel surfaces. Conclusion: Acceptable bond strengths were obtained with Icon application as measured in vitro, producing the highest strength of all tested sample when compared with the other adhesive system without Icon.