Scoliosis is a lateral curvature of the spine. It is the most common deformity of the immature spine. The essential goal of treatment is to allow patients with scoliosis to avoid cardiopulmonary and neurological problems, and to improve the patient's appearance and future quality of life. Kinesio Taping is a method used for treatment of various musculo-skeletal conditions. The effects of Kinesio Taping is to relieve pain or abnormal feeling on the skin and fascia, supports the muscle in movement, removes congestion of lymphatic fluid or hemorrhages under the skin, and corrects misalignment of the muscle, fascia, and joint. Forty adolescent females complain from scoliosis their ages ranged from 11 to 17 years old, and their BMI was from 15 to 25 kg/m². They were divided randomly into two groups. Group A received therapeutic exercises for scoliosis, while group B received therapeutic exercise in addition to kinesio taping. X ray plain used for measuring of Cobb’s angle and present pain intensity (Ppi) for pain assessment before and after treatment. There was a significant reduction of Cobb's angle and pain intensity at post treatment at both groups (p<0.05). There were significant reduction p<0.0001 in Ppi and this significant reduction in favor of group B. There was no significant differences between both groups in Cobb’s angle. Exercises for scoliosis and exercises augmented by kinesio taping had a significant effects on reduction of both Cobb’s angle and pain intensity.