Background: Patellofemoral Pain Syndrome (PFPS) is one of the most common knee complaints of both the young active sportsperson and the elderly. It often affects the function activities of an individual. Purpose: The purpose of the study is to compare the effectiveness of weight bearing and non-weight bearing exercises versus weight bearing quadriceps strengthening exercises in patella femoral pain. Design: A Randomized clinical trial Setting. The study was conducted at a tertiary care hospital. Subjects: 34 subjects with PFPS, between 18-42 years were recruited based on symptoms and Clark’s Test. Intervention: Group A received conventional treatment along with weight bearing exercises and group B also received conventional treatment along with weight bearing and non-weight bearing exercises. Measurements: Subjects were assessed at baseline using Visual Analogue Scale (VAS), Quadriceps Strength assessed using HHD and functional ability using AKPS and re-assessed after 09 sessions. Results: The difference between the two groups was statistically significant in terms of pain, Quadriceps strength and functional ability with p<0.05. Conclusion: Along with exercises, IFT and Taping helps in the reduction of pain. Thus, improving the ability of the individuals affected performs better in ADL’s or athletic performance.