Nosocomial infections are infections that are not present in the patient at the time of admission to hospital but develop during the course of the stay in the hospital. Nosocomial infection, is a serious health center problem that cause to increase medical costs and mortality all over the world. Environment and Personals of hospitals are the most reservoir and vehicles for the transmission of microorganisms. This study had been conducted to identify the types and sensitivity of bacterial isolates to commonly used antibiotics. For the period from the April 2012 to April 2015 collected 2208 samples of personals and all wards of two hospitals in two of hospitals in Kermanshah province ,western Iran.