Promotion, as well as maintenance of health, is directly associated with exercise and good dietary habits. Lack of exercise and good dietary habits adversely affect health, therefore this study was conducted to assess the perception of patients regarding the effectiveness of exercise and medicine in the maintenance of health. Total of 30 patients of different diseases (heart diseases, hypertension, and obesity) was voluntarily taken as a sample of the study. For the collection of data, a questionnaire was developed; collected data were analyzed by applying Student’s t-test using SPSS version 21.0. Heart problems, hypertension, and obesity all are the chronic health problems and the majority of the respondents opined that the impact of performing various kinds of exercise along with medicine for reducing these chronic health problems was significant (p=0.004). On the basis of findings, the researcher concluded that exercise is the sister art of medicine which plays a significant role in preventing different health problems such as heart diseases, hypertension, and obesity.