Objective: This study was done to compare the fluoride release from dental adhesive systems (total etch Tetric N-bond and self-etch Tetric N-bond) with the addition of fluorapatite or calcium fluoride in percentages that didn’t affect its original shear bond strength for 89 days in vitro. Materials and methods: From each material, 10 cylindrical disk-shaped specimens (diameter: 8.0 mm, height: 1.0 mm) were prepared and immersed individually in 10 ml of deionized water in plastic containers. After 1, 2, 4, 7, 14, 21 and 28 days and after 1 month and 2 months from the last measurement the samples were transferred into new plastic containers that contained 10 ml of deionized water to measure the amount of fluoride in it. The fluoride content was determined with Fluoride Ion Selective Meter HI 96729. Results: The mean fluoride ion release from each material over the tested periods was recorded and the data were statistically analyzed with ANOVA and LSD tests. Self-etch Tetric N-bond with 7% of its weight of calcium fluoride addition showed the greatest fluoride release over the tested periods among the tested material. Conclusion: All the tested materials with the addition of fluorapatite or calcium fluoride showed highest fluoride release during the first two days.