Background: It was reported that intermittent fasting has several health benefits. Therefore, the present study aimed to assess the hemodynamic variations associated with Ramadan fasting among Saudi Stroke patients. Methodology: Information referring to 61 stroke patients were retrospectively retrieved from King Khalid hospital, Hail, Northern Saudi Arabia. Data relating to patients attended during the period from April 2019 to June 2019. The sample involved two months (Shaban and Ramadan) a full coverage sample. Results: Out of 61 study subjects, 26 patients were fasting during stroke happening and 35 patients were non-fasting. Out of the 61 patients, 35 (57.4%) were females and 26 (42.6%) were males. With the fasting month, hypertension was co-occurrence in 23/49 (47%) fasting patients, hence, it occurred in 26/49 (53%) among non-fasting patients, the risk of hypertension during Ramadan compared to nonfasting month; the relative risk (RR) and 95% confidence interval (95% CI): RR (95%CI)=1.1908 (0.9374 to 1.5128). Conclusion: Ramadan Fasting has some beneficial effects influencing stroke including incidence and severity reduction. Stroke associated hemodynamic variants, which were more apparent among women, were perceived to decline during fasting.