Abstract

Hyponatremia and Hypokalemia Prevalence in Tuberculosis Patients in a Teaching Hospital.

Author(s):Ryhan Uddin1*, Fayyaz Uddin2, Talha Mufeed1, and Faheem Jan3

Summary: Study is conducted on tuberculosis patients admitted to a teaching hospital and deals with serum electrolytes profile analysis. Study shows prevalence of hyponatremia (56.2%) and hypokalemia (28.4%) in tuberculosis patients receiving anti-tubercular therapy. Background: Tuberculosis is a contagious chronic disease caused by mycobacterium tuberculosis affecting millions of people worldwide. Although primarily known impact on respiratory system, tuberculosis can lead to systemic effects including serum electrolytes imbalances. Objective: Aim of the study is to analyze serum sodium and potassium concentrations of tuberculosis patients on anti-tubercular therapy in a teaching hospital to evaluate their imbalances. Patients and Procedures: The study is conducted on 169 patients of Pulmonary Tuberculosis (PTB) in the Department of Pulmonology, Khyber teaching hospital, Peshawar from January 2018 to June 2022. The patients were going through anti-tubercular therapy. Demographics and laboratory tests were collected from the patient’s hospital profile and analysis was done through GNU Project Statistical Programing Platform (GNU PSPP). Laboratory tests were performed during their stay at hospital. Results: The mean age was 46.29 ± 19.91 years and 51.5% of the patients were female. The mean serum sodium concentration was 133.31 ± 7.93 mmol/L and mean serum potassium concentration was 3.93 ± 0.87 mmol/L. Prevalence of hyponatremia and hypokalemia were recorded as 56.2% and 28.4% respectively. No statistically significant correlation found between variables with no statistically significant value of p. Conclusion: There is decrease in the level of serum sodium and potassium concentrations in tuberculosis patients.

• PDF