Background: Implementing early detection’s sustainable programs of breast cancer is fundamental for better disease management. Therefore, the present study aimed to assess the insight of Saudi women towards Breast self-examination (BSE) in Qurayyat, Northern Saudi Arabia. Methodology: This descriptive study included 620 Saudi volunteers living in the city of Qurayyat, Northern Saudi Arabia. Women who denied to participate in the breast self-examination workshop were included for perception assessment. Results: A previous BSE was experienced by 217/620 (35%). “Previous knowledge about BSE”, (response=536) good knowledge 217 (40%), poor knowledge 208 (39%), know nothing 111 (21%). Conclusion: There is relatively lower knowledge regarding BSE and its related factors in Northern Saudi Arabia. Saudi Northern women have positive attitudes towards health education and training on BSE.