Logo

International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)

Abstract

Isolation and identification of pharmacologically active compounds in fruit of Pyrus pashia

Author(s):Subhash Chandra, Sarla Saklani and Rohit K. Agrawal

The aim of this work is to investigate pharmacological active compounds analysis and their anti-inflammatory activity of Pyrus pashia fruit. In this work some pharmacological active compounds were isolated by column chromatographic techniques and identification of their structure by spectroscopic (NMR, IR, Mass, UV, etc.) methods. Lupeol, β-Sitosterol and β-Sitosterol –ß-D glucoside compounds were isolated. These compounds firstly were isolated from Pyrus pashia fruit. The anti-inflammatory activity of these compounds has been investigated with in vivo study. In this study, it has been shown that Pyrus pashia isolated compounds showed potent antiinflammatory activity. The active ingredient in the extract that reduces the inflammation is not known at present. There is ongoing research to isolate and characterize the bioactive compound (s) responsible for the antiinflammatory activity of Pyrus pashia.


Scope Categories
  • Clinical Research
  • Epidemiology
  • Oncology
  • Biomedicine
  • Dentistry
  • Medical Education
  • Physiotherapy
  • Pulmonology
  • Nephrology
  • Gynaecology
  • Dermatology
  • Dermatoepidemiology
  • Otorhinolaryngology
  • Ophthalmology
  • Sexology
  • Osteology
  • Kinesiology
  • Neuroscience
  • Haematology
  • Psychology
  • Paediatrics
  • Angiology/Vascular Medicine
  • Critical care Medicine
  • Cardiology
  • Endocrinology
  • Gastroenterology
  • Infectious Diseases and Vaccinology
  • Hepatology
  • Geriatric Medicine
  • Bariatrics
  • Pharmacy and Nursing
  • Pharmacognosy and Phytochemistry
  • Radiobiology
  • Pharmacology
  • Toxicology
  • Clinical immunology
  • Clinical and Hospital Pharmacy
  • Cell Biology
  • Genomics and Proteomics
  • Pharmacogenomics
  • Bioinformatics and Biotechnology
  • Recommended Conferences

    International Conference on Haematology and Medical Oncology

    Edinburgh, Scotland

    Medical Summit and Expo on Healthcare and Medicine

    London, United Kingdom