Background: HIV/AIDS affects the most productive age group, the knowledge of which is clouded with many myths and misconceptions. Objective: To determine the knowledge and awareness about various aspects of HIV/AIDS among the students of MBBS first year. Methodology: The students were asked to fill a pre-designed, structured, semi open ended questionnaire. All efforts were made to ensure the originality of the responses. Statistical Analysis: The data collected so, was analysed, tabulated and presented in the forms of percentages and proportions. Appropriate statistical tests applied, wherever applicable. Results: Among the total of 122 respondents, all of them have heard about HIV/AIDS and that it is caused by a virus. About 43.4% students believed that HIV infection means AIDS. The place where HIV testing is done, was known to about 78%. Knowledge about the routes of spread included; through infected injections (100%), through blood transfusion (98%), Unprotected Sexual contact (97.5%), Infected Mother to child (86%). The respondents were aware that it doesn’t spread through touching/hand shaking (99.2%), sharing food (93.4%), using common cups/glasses (89%), used clothes/towels/soap (88.5%). About 80% responded to have discussed about HIV/AIDS ever with anybody, while about 82% considered safe working with a patient of HIV/AIDS. Conclusion: Most of students were aware about the basic knowledge while they also had a misconception which implies that the students should be equipped more, especially since the beginning of their career.