In severe leptospirosis multi organ involvement is common. Pancreatitis and meningo encephalitis are two uncommon manifestations of leptospirosis. Our patient presented with fever, jaundice, altered sensorium and subsequently developed severe pain abdomen. He was finally diagnosed as having icteic leptospirosis complicated with pancreatitis and meningoencephalitis. Simultaneous presence of these two complications in a patient of leptospirosis probably not been documented before.