Mechanical properties (impact strength, compressive strength and flexural strength) have been studied for (Polymethyl-methacrylate (PMMA)) polymer reinforced with nano (TiO2+ZnO) (0 v%, 1 v%, 2 v%, 3 v%, 4 v% and 5 v%). Ultrasonic dispersion technique was used to prepare the nanocomposites samples, follow with cold casting technique using Teflon molds standard conditions. Charpy impact instrument was used to measure the impact strength, the compressive strength of each sample which was tested in newton units using digital compression tester (TinusOlsen: H50KT, England), while flexural strength can be found from mathematical formulas which depend on the impact strength, compressive strength and flexural strength. Results show that values increase in 1 v%, then decrease alternately by (2 v%, 3 v%, 4 v%, and 5 v%), while 0 v% is the less value of volume fraction of fillers. Young modules values increase alternately by the volume fraction of fillers until 2 v%, while if it is higher and lower than 2 v% it decreases the modulus of elasticity.