Ewing’s Sarcoma (ES) mainly affects the second decade of life with long bones as the preferred site. Chromosomal translocation of t (11;22) is the most common abnormality associated with it. The spine is rarely involved and most commonly sacrum is involved. Non-sacral ES is rare and especially in middle age. We hereby report a case where a 46-year female had L2 vertebral pathological fracture (due to non-sacral ES) and presented as acute paraparesis.
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