Nursing Professional Regulation is one of those concepts that use of it in nursing has become popular in recent decades all over the world; since training has an undeniable role in preparing staff to enter the profession and compliance with scientific and technological changes, the present research has been conducted aiming at determining the nursing educational regulation model. The present study was performed using qualitative systematic review (meta-synthesis). Search is made by keywords such as training regulation setting, nursing, Regulatory and legislative setting of databases PUBMED, Science Direct, Ovid, ProQuest. After examining 585 articles, ultimately 10 articles and 1 Statement on the World Health Organization were selected. The inclusion criteria include English and Persian language and being associated with the regulation of nursing education. Firstly the articles have been examined based on their title and summary and included in the study under having the inclusion criteria. In the next stage, quality of qualitative articles which had been introduced via instruments for critique of qualitative studies by Ryne et al.(2007) has been examined by other researchers in separate. The articles which were diagnosed suitable from point of view of two persons were included in the study and analyzed. Data analysis was made via Thematic analysis. To improve accuracy of data, research method was used and the data were analyzed by the researcher. Two major duties by educational regulation entities are educational planning and monitoring education. In educational planning, an emphasis has been put on training students to enter into profession and educational planning has adapted well suited to the changes in society; in educational monitoring, focus on confidence on the effective training and gaining the early required skills to enter into the practice and confidence on maintaining and developing the staffs’ clinical skills are well suited to the needs and conditions of the society by evaluating the staffs’ professional competence at the early of arrival to practice. Nursing educational regulation implies formulating, regulating and approving the rules and standards of professional nursing education to develop and maintain the staffs’ skill and competence based on the conditions and needs of society and improvement in quality of care to achieve safe care in the society.