Regulation is one of the concepts that has been common in nursing in recent decades. Concept analysis of nursing regulation by providing a clear definition will promote nursing knowledge and professionalization. This study aims to clarify the concept of nursing regulation through the use of Rodgers's evolutionary approach. The keywords, regulations, regulatory system, regulatory body, regulatory authorities, legislation and nursing were used from PUBMED, Google Scholar, ProQuest, science direct electronic databases. Literature published in English between 1980- 2015 that addressed regulation was included. 30 articles, 3 statements of the WHO and ICN reports were selected. 2 articles about legislation in Iran and a statement of health revolution in Iran were considered. Thematic analysis was used to distinguish attributes, antecedents, and consequences of the nursing regulations. Attributes of nursing regulation were dynamic, cyclic, purposeful, flexible, relevant, ultimate, consistent, fair, integral, efficient and expressing an effective; its antecedents are in accordance with the need and demand of the society, influenced by contextual conditions and governance structure, constructive engagement of regulatory agencies and members of the profession, professional responsibility of and effective staff training and its consequences include promoted health of the society, assurance about the provision of safe and effective services, promotion of authority and professional independence, increased compatibility and collaboration between professionals and reduce the challenges posed by the lack of interaction between professionals. Nursing regulation is the essential component of care and it ensures the provision of a very high quality care which is ethical and safe.