Lichen planus is a chronic, inflammatory, mucocutaneous autoimmune disease that affects various surfaces such as the mucous membrane of the oral cavity, genitalia, skin, nail scalp esophagus, and eye. The lesion may affect many sites and at the same time, it may affect inter and extra orally. The lesion appears as a sequence of different types of lesion mostly intra orally and extra orally. The lesion may be associated with symptoms of pain and burning or with candida growth. Objective: To evaluate a correlation between oral LP with age, GLP changes among Iraqi females patients, to isolate and identify Candida species from the mucous membrane of LP patients and to find its role to aggravate these symptoms and its effects on the clinical investigation in that individual who had been used carrageenan for treatment burning sensation. Material and methods: The study was performed at the college of dentistry, University of Baghdad. The sample consisted of 15 LP patients. Candida species were isolated from the oral cavity of patients (affected and unaffected sites). Results: The most frequent affecting age was 45-54 and the buccal mucosa was the most commonly affected site. The lesion was the Bilateral, symmetrical and reticular type of lesion appeared in 73.3% cases. Burning sensation at the buccal mucosa was the most prevalent complain of about 86.6 patients while 2/3rdof the sample had genital symptoms. The vulval lesion was present in about 60 of genital lesions. High significant correlation was found between the genital lesion and the site of OLP lesion at buccal mucosa and gingiva. Carrageenan showed strategies to treat OLP symptoms. Candida growth was more at the affected site of OLP lesion than the normal site of the same patient. This may give an indication about its role in incidence and aggravation of lesion. Conclusion: The diagnosis and management of LP lesion can be challenging for oral medicine and gynecologist specialist because of the lack of familiarity between these two branches and patient embarrassment in history recording. Therefore, genital LP should be considered among individuals with oral LP lesions.
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