Whey Protein (WP) and other protein-fortified supplements are frequently recommended as nutritional supplements to aid in muscle hypertrophy and myogenesis during resistance training. This case report presents a 36 year-old athletic male with elevated creatinine and uric acid levels during routine laboratory evaluation. The patient had no history of kidney disease, diabetes, or hypertension. Upon further examination, it was revealed that the patient had been regularly consuming whey protein as a dietary supplement for two months. Given the potential association between the elevated creatinine and uric acid levels and the use of whey protein, the patient was advised to discontinue the supplement. The patient then switched to protein-fortified milk in an effort to mitigate the possible harmful connection between the dietary intake and the laboratory findings. However, despite the dietary change, the increased levels of creatinine and uric acid persisted. This observation suggests that the elevated levels may be attributed to chronic whey protein consumption along with high protein dietary consumption. The case highlights the potential adverse effects of protein supplementation, particularly whey protein, on renal function.
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