Predicting Urinary Tract Infection in Jaundiced Newborns by Phototherapy Response | Abstract

International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)


Predicting Urinary Tract Infection in Jaundiced Newborns by Phototherapy Response

Author(s):Fatma Simsek, S. Umit Sarici, Demet Soylu*, Muhittin A. Serdar, Murat Ozcan and Dilek Sarici

Objective: This study aimed to compare the post-phototherapy decrease in Serum Total Bilirubin (STB) levels of newborns diagnosed to have idiopathic pathologic hyperbilirubinemia with and without Urinary Tract Infection (UTI) and to determine a critical cut-off value of percent decrease in STB with phototherapy in predicting the diagnosis of UTI. Methods: Urine samples for microscopic examination and bacteriologic culture were obtained in 381 newborns of whom all other possible etiologic causes of neonatal hyperbilirubinemia were excluded. Newborns with and without positive urine culture (Groups I and II) were compared concerning demographic findings and laboratory data. The Receiver Operating Characteristic (ROC) curve was constituted. Results: Post-phototherapy STB level was significantly higher (P=0.0002) and the decrease in STB level with phototherapy was significantly lower (P<0.0001) in Group I when compared to Group II. The critical cut-off value of STB decrease in predicting UTI was 47.9%. Conclusions: A relatively inadequate phototherapy response (STB decrease of <47.9%) should raise the suspicion of UTI, and further urine examinations should be performed considering that 40% of newborns with a decrease of <47.9% in STB despite phototherapy may have UTI and 90% of those with a decrease of ≥ 47.9% do not have UTI

Select your language of interest to view the total content in your interested language

Scope Categories
  • Clinical Research
  • Epidemiology
  • Oncology
  • Biomedicine
  • Dentistry
  • Medical Education
  • Physiotherapy
  • Pulmonology
  • Nephrology
  • Gynaecology
  • Dermatology
  • Dermatoepidemiology
  • Otorhinolaryngology
  • Ophthalmology
  • Sexology
  • Osteology
  • Kinesiology
  • Neuroscience
  • Haematology
  • Psychology
  • Paediatrics
  • Angiology/Vascular Medicine
  • Critical care Medicine
  • Cardiology
  • Endocrinology
  • Gastroenterology
  • Infectious Diseases and Vaccinology
  • Hepatology
  • Geriatric Medicine
  • Bariatrics
  • Pharmacy and Nursing
  • Pharmacognosy and Phytochemistry
  • Radiobiology
  • Pharmacology
  • Toxicology
  • Clinical immunology
  • Clinical and Hospital Pharmacy
  • Cell Biology
  • Genomics and Proteomics
  • Pharmacogenomics
  • Bioinformatics and Biotechnology