Background: The prevalence of smoking has reduced over a period of time in the developed countries. However, the consumption of tobacco is rapidly increasing in the developing nations which further raises burden of various diseases. The prevalence of consumption of tobacco among the adolescent population is vigorously growing across the world. There are several studies in Saudi Arabia that report the smoking rate and pattern among the secondary school students, but very limited data is available about the prevalence of smoking among the college students. Therefore, the objectives of the current study are to assess the prevalence of smoking among the male college students and to evaluate the relationship between the smoking habit and socio-demographic variables. Methodology: This was a cross-sectional study done in selected colleges in King Khalid University, Abha during August 2016 to December 2016. A structured questionnaire was used to collect the socio-demographic information and about smoking habit among the college students. Results: The study showed 18.7% of prevalence of smoking among the male college students with a positive association between employment and smoking habit. However, no positive association between other socio-demographic variables and smoking. Conclusion: Though the prevalence rate of smoking among the male college students is less but still there is a need to create awareness among the college students and their parents for decreasing the burden of tobacco related diseases.