Abstract

Proposed Vaccine for Mental Health: From Green Tea

Mental health is one of the major concerns prevailing now-a-days, both, at national level and global level. Specially, after COVID-19, this concern has raised to an alarming level, and needs to be worked upon. Although, there are various therapies and medications against mental disorders. But, those medicines have their own side effects also. We need to take some extra step towards the root of these mental disorders, which is ‘psychological stress’. Psychological stress is not only the root of various mental disorders, but also, a few physical health issues, such as type-2 diabetes mellitus, cardiovascular diseases, cancer, etc. That’s why; we do need therapeutic agents and their target against psychological stress. A few publications on PubMed claimed that, green tea has a few such natural components. Two phytochemicals of green tea ‘caffeine’ and ‘L-theanine’, acts on brain, and can positively influence mood and cognition. Both these components in this research were studied using ‘PubChem’ and ‘ADMETlab2.0’. Caffeine mainly enhances arousal, alertness, and, attention-switching. While, L-theanine can increase the level of happiness promoting neurotransmitters in brain, which are serotonin, dopamine and GABA, as suggested by ‘PubChem’. ADMETlab2.0 suggests the overall safety of both these phytochemicals on human body. So, the final conclusion of this research was that, mainly ‘L-theanine’ as key component or ‘L-theanine’ and ‘caffeine’ together, isolated from green tea, can serve as ‘preventive or therapeutic vaccine’ against various mental disorders and psychological stress

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