Introduction: Patient safety culture is the first necessary step to reduce medical errors and improve patient's condition. In this context, this article aims at studying the condition of patient safety culture in hospitals in Elam in 2016. Materials and Methods: In this cross-sectional study, 150 nurses in Ilam were randomly selected. The Culture Hospital Survey on Patient Safety (HSOPSC) was used and its reliability and validity had been confirmed by the previous studies. The data were analyzed by SPSS17. Results: The results showed that the nurses' safety was at positive(62.37± 8.70) and there could be found no significant difference in patient safety among the studied hospitals in this article (P<.05). Extra-organizational teamwork and non-punitive response, among the aspects of patient safety, had the lowest means and organizational learning and general understanding had the highest. Conclusion: Considering the importance of patient safety, the interventions need to be performed in order to improve the patient safety condition among nurses, especially in two aspects of extra-organizational teamwork and non-punitive response that had the lowest means.