Abstract

Surgically treated early stage cervical cancer - Prognostic factors and adjuvant treatment

Author(s):Verneker Ruchika A, Desai Arun J and Patel Shilpa M

Invasive cancer of cervix is considered a preventable disease as it has a long pre-invasive state. If detected in early stages i.e upto stage IIA1 the disease is curable with good survival rates. · To identify the prognostic factors in surgically treated early stage cervical cancer · To study if preoperative findings could accurately predict presence of poor prognostic factors such as nodal status · To evaluate these histological prognostic factors in deciding the further management of patient with adjuvant treatment This is a prospective study of prognostic factors and adjuvant treatment in 60 cases of surgically treated early stage cervical cancer (Radical hysterectomy with bilateral pelvic lymph node dissection).Histo-pathological findings were evaluated to determine the prognosis.Result:25% patients had lymph node involvement and lymphovascular space invasion was seen in 15% of cases. Parametrium was involved in 16.6%. There were 3 patients with positive margins and 65% patients had moderate differentiation of tumor. Maximum number of nodes were positive in stage IB2. Size of the tumor more than 4 cm is an important determinant of prognosis and has an definite effect on lymph node metastasis and other poor histological prognostic factors. • Adjuvant treatment is must incase of patients with intermediate or high risk prognostic factors

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