The Effect of iv. Lidocaine On Postoperative Respiratory Comlications of Isoflurane Anaesthesia In Paediatrics | Abstract

International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)


The Effect of iv. Lidocaine On Postoperative Respiratory Comlications of Isoflurane Anaesthesia In Paediatrics

Author(s):Mustafa Mohammed Salih*, Afraa Kasem Kadhim and Hussein Talib Mohsin

Background: Inhalation anesthesia using Isoflurane in pediatrics is related to airway irritability, coughing, breath holding, and laryngeal spasm. This study aims to determine the effect of i.v. Lidocaine 5 minutes before emergence on the incidence and severity of postoperative respiratory complications of Isoflurane in a pediatric population. Method: A randomized clinical trial study conducted in Children Welfare Hospital included 118 unpremeditated children, aged 6 months to 10 years who were enrolled in the study and randomized to receive iv. Lidocaine (n=54, Group A) and Not receiving Lidocaine (n=64, Group B). Were all induced with Propofol and maintained with Isoflurane. The occurrence of coughing, breath-holding, laryngospasm, bronchospasm, and secretion was recorded. The severity of each complication was graded on a scale of 0-3. Results: The incidence of coughing (31% vs 56%) and laryngospasm (22% vs 59%), coughing severity score (26 vs 72), breath-holding severity score (16 vs 38), and the need to change to a higher FiO2 (4% vs 11%) were more frequent in Group A than in Group B (p<0.05). There was no difference regarding the incidence of breath-holding (26% vs 31%) and secretion (30% vs 31%). Conclusions: i.v. Lidocaine 5 minutes before emergence from anesthesia reduces the frequency and severity of coughing, the frequency of laryngospasm, the severity of breath-holding, and the need to change to higher FiO2 in pediatrics.

Select your language of interest to view the total content in your interested language

Scope Categories
  • Clinical Research
  • Epidemiology
  • Oncology
  • Biomedicine
  • Dentistry
  • Medical Education
  • Physiotherapy
  • Pulmonology
  • Nephrology
  • Gynaecology
  • Dermatology
  • Dermatoepidemiology
  • Otorhinolaryngology
  • Ophthalmology
  • Sexology
  • Osteology
  • Kinesiology
  • Neuroscience
  • Haematology
  • Psychology
  • Paediatrics
  • Angiology/Vascular Medicine
  • Critical care Medicine
  • Cardiology
  • Endocrinology
  • Gastroenterology
  • Infectious Diseases and Vaccinology
  • Hepatology
  • Geriatric Medicine
  • Bariatrics
  • Pharmacy and Nursing
  • Pharmacognosy and Phytochemistry
  • Radiobiology
  • Pharmacology
  • Toxicology
  • Clinical immunology
  • Clinical and Hospital Pharmacy
  • Cell Biology
  • Genomics and Proteomics
  • Pharmacogenomics
  • Bioinformatics and Biotechnology