Breakdown in emotional relationships increased the possibility of mental health problems for people. Love Trauma Syndrome is a painful experience that occurs after the collapse of a romantic relationship and disturbed individual’s performance in multiple areas. Schema Therapy is an integrated approach that can help reduce the symptoms of emotional breakdown in people. This study aimed to investigate the effectiveness of schema therapy on alleviates symptoms of emotional breakdown. This was a Single-subject study. The study subjects were three women of college students who studied in different universities in Tehran and refer to college counseling centers to release of their emotional breakdown symptoms. the samples were selected by Purposeful sampling method to take part in16 individual sessions of schema therapy. Variables measured at 3 main stages of experiment processincluding3 measures as baselines, four measures during therapy sessions and3measures as follow-up, by Dehghani’s Love Trauma Syndrome questionnaire (1389). In addition, in pretreatment stage the participants were completed love trauma Rossee questionnaire (1999) and millon -3questionnaire. The data were analyzed by the graph changes, clinical significance, and the index of improvement percentage. The findings showed that schema therapy have been effective in reducing symptoms of emotional breakdown. As a result, this intervention can be effective in reducing symptoms of emotional breakdown.