Aging is a period in which people, while basically unattended by others, are more exposed to stressors and various pressures of life. This study was, therefore, targeted to reveal the effects of hope therapy on depression and the life quality of the aged people in day care centers of Mehriz, a town in Yazd province, in 2013. The statistical population of this research embraced all the elderly in day care centers in Mehriz. The sample size included 24 elderly women who were assigned to two experimental (12) and control (12) groups. The present study enjoyed apretest-posttest quasi-experimental design. The instrument used in the study was a questionnaire on the elderly depression (G.D.S).The results of the covariance test revealed that there was a significant difference between the experimental and control groups. The hope therapy played a significant role in alleviating the elderly depression level. The results generally indicate that such a therapy can be regarded as an efficient remedy in decreasing the elderly depression.