Diabetes is one of the chronic diseases causing the deaths in human societies. Since the patients suffering diabetes are prone to many complications, self-care will be one of the most effective ways to prevent these complications. The current study aimed at evaluating the effect of implementation of hospital discharge planning on the self-care ability of the patients suffering type-2 diabetes in the hospitals supervised by Shiraz Medical University in 2013. The current study is a semi-experimental study of clinical trial type. The participants were 66 patients with typediabetes which were divided into case (33 patients) and control (33 patients) groups. For the case group, the discharge plan was performed using oral instructions, booklet, and telephone counseling while the patients in the control group received routine care. The self-caring abilities of the patients were measured using a standard questionnaire pre- and post-intervention. The descriptive and analytical statistics tests through SPSS16 were used for data analysis. The average score of the self-care in the control group was 23/17 ± 48/69 pre-test and 17/12 ± 72/47 post-test which were statistically significant. The average score of the self-care in the case group was 23/17 ± 48/69 pre-test which was increased to 17/12 ± 72/47 post-test (p<0.001). There were no significant differences between the scores of self-care between the case and control groups before the implementation of discharge plan (p.0.05). After the implementation of the discharge plan, there were statistically significant differences in scores of self-care ability between the case and control groups. Also, there was a significant relationship between the selfcare ability and the patients’ income. The results of the study indicated that the implementation of discharge plan for the diabetic patients can lead to an increase in self-care abilities. Accordingly, it is recommended this low-cost method be used for improving the patients’ self-care abilities and consequently reducing the complications associated with diabetes.