The present study aims to investigate the impact of Deep Venous Thrombosis (DVT) education on improving the therapeutic outcomes among DVT patients. For this purpose, 150 patients diagnosed with DVT were recruited from Rafha General Hospital to conduct a cross-sectional descriptive study. The present study evaluates the following therapeutic outcomes; health status, drug compliance, and quality of life which were excellent in 90%, 91%, and 88% of DVT patients who have an acceptable level of knowledge about their medical condition, respectively. On the other hand, previously mentioned therapeutic outcomes were excellent in only 20%, 24%, and 20% of DVT patients who have a non-acceptable level of knowledge about their illness, respectively (p<0.05). The results of our study pointed out that an increased level of knowledge of DVT patients regarding their medical condition was associated with excellent therapeutic outcomes. We tried to encourage our participants to acquire essential knowledge about their medical conditions. Furthermore, this study provides us with a clear idea about the impact of health education on therapeutic outcomes among DVT patients for current evaluation and future implementation of programs aiming towards achieving excellent therapeutic outcomes through proper health education of DVT patients.