Recently, obesity has become an important worldwide health problem. One of the obesity treatment alternatives is bariatric surgery methods and their efficiency is increasing from day to day. In laparoscopic Sleeve gastrectomy being a bariatric surgery method, as a result of stomach fundus excretion, levels of some hormones change. Therefore, weight losses seen after the treatment are related to these changes. Basically, it is claimed that, after laparoscopic Sleeve gastrectomy, levels of ghrelin hormones secreted by stomach fundus, being effective for appetite and getting foods change. Although there are many studies examining varieties of ghrelin levels after laparoscopic sleeve gastrectomy, there is no final judgment concerning the subject yet. In this review, in the light of literature knowledge, giving information regarding effects of laparoscopic sleeve gastrectomy on ghrelin levels is aimed.