Abstract

The Sperm Vitality Test with Eosin-Nigrosin can be used as an Indicator of Globospermia Type III

Introduction: Teratozoospermia is characterized by the presence of spermatozoa with abnormal morphology in sperm. Globozoospermia is a rare (incidence 0.1%) and severe form of teratozoospermia characterized by the presence in the ejaculate of a large majority of round spermatozoa without acrosome. Globozoospermia is most commonly caused by mutations in the DPY19L2 gene. Globozoospermic spermatozoa are thus unable to adhere and penetrate the zona pellucida, causing primary infertility. Results: Total teratozoospermia 100% (globozoospermia 89% and other forms of abnormal morphology 11%), necrozoospermia 69%, asthenozoospermia 99%. Conclusion: The case presented is the first to be published as a pathology of infertility in the Republic of Kosovo. Teratozoospermia in the form of globozoospermia was 89%, and we called it globozoospermia severe or Globospermia type III, based on the results of 100% atypical morphology (89% globozoospermia +11% other atypical forms) and necrozoospermia 69% as well as asthenozoospermia 99%.

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