This study examined the attitudes of head nurses toward nurses' performance in special and general wards in instructional hospitals of Zahedan .Nurses have different roles in providing nursing cares .since prevention is one of the important goals of nursing cares. They take care of people with physical, mental, social and emotional aspects. These people have special needs which are associated with each of these dimensions. This study purpose is to examine the views of head nurses and to recognize strengths and weaknesses of these wards for planning right things to do. The aim of this study was to assess the performance quality of nurses, from the viewpoints of headnurses in special and general wards in instructional hospitals Zahedan city. This study is a cross sectional analytic study. In the study 252 graduated nurses who were working in the special and general wards of instructional hospitals in Zahedan were selected during the study .sampling was census 102 nurses were selected in special wards and 150nurses in general wards were selected randomly. The questionnaire was a ministry health checklist which was given to all head nurses for assessment. Statistical analysis was done using Pearson correlation and T test. Based on study results, quality performance scores of the nursing in special and general wards were respectively 103/1 and 109/2. There was a Significant statistical difference between the mean of nursing quality performance in special and general wards (p<0/001). A significant statistical correlation was observed between experience and the nursing performance quality score (p=0/03/ c=0.17). For each year of experience performance score has increased by 0/17. Results showed that the score of nurses' performance in special wards was lower than general wards and since nursing care is more specialized in special wards and patients are dependent to nurses, it is necessary to improve the strengths and omit the weaknesses for proper planning.