The researchers have come to know the concept of the job satisfaction as a general satisfaction in the majority of the occupational conditions such as payment, promotion, security and so on. Job satisfaction is one of the main factors influencing the occupation’s favorable aspects including organizational commitment, improving the organizational citizenship behavior, elevating the customers’ satisfaction and reducing the frequent absences from work. Therefore, the current study aims at the survey of the job satisfaction rate in the nurses working in the training hospitals associated with Zahedan medical sciences university. The present study is a descriptive-analytical research which has been conducted on 264 nurses. The required information have been collected through the use of a two-part questionnaire the first part of which related to the demographic characteristics and the second part encompassed a researcher-made job satisfaction questionnaire. The data extracted were analyzed by the use of descriptive statistics methods, independent t-test and variance analysis in SPSS 19.0 software. In the present study the participants average age was 32.61 ± 6.95 and 185 individuals (70.1%) were women. The nurses overall mean score for the job satisfaction was 65.41± 11.58. Three individuals showed a very low level of job satisfaction, 19 individuals indicated low satisfaction, 53 individuals were satisfied and 5 individuals were completely satisfied with their jobs. Generally speaking, 89 individuals were dissatisfied with their jobs and the rest were happy with their jobs. The relationship between job satisfaction and participants’ age and gender was found to be statistically significant. The results of the study indicated that the nurses’ job satisfaction was in an intermediate level and a considerable percent of the nurses were dissatisfied with their jobs.