International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)
Alaa Fadhil Alwan
Baghdad University, College of Medicine,Baghdad, IraqPublications
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Research
Hyper-CVAD Protocol versus UKALL Protocol and the Minimal Residual Disease Status in Adult Acute Lymphoblastic Leukemia Patients
Author(s): Ahmed Mjali*, Bassam Francis Matti, Yassmin Ali Abdul Kareem, Dhulfiqar Azeez Hasan, Anmar Alharganee, Alaa Fadhil Alwan, Aladdin Sahham Naji, Tareq Abdullah Saleh, Amer Shareef Alhachmi, Ibrahim Khalil Al Shemmari, Haider Hasan Jaleel Al- Shammari, Talib Hussein Kamoona, Nareen Tawfeeq Abbas, Saja Khudhair Abbas and Ahmed Ibrahim Shukr
Introduction: In Iraq acute lymphoblastic leukemia (ALL) represents the most common hematological malignancy contributing 41% of all leukemia cases. Hyper-CVAD protocol and UKALL protocol are commonly used in ALL treatment. In this study, we tried to assess minimal residual disease (MRD) post induction therapy for both hyperCVAD protocol and UKALL protocol by using 8 colors flow cytometry. Material and Method: Data collected retrospectively from 85 adult patients with acute lymphoblastic leukemia (≥ 14 years old) received either hyper-CVAD or UKALL chemotherapy protocol, with MRD level results post induction therapy of each protocol therapy, from January 2017 till October 2019. Fifty patients (58.82%) with B-ALL, while T-ALL were 35 patients (41.18%). Patients treated with hyper-CVAD proto.. Read More»
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