International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)
Arun Tyagi
Department of Medicine, DVVPF’s Medical College, Vadgaon Gupta, Post-MIDC, Ahmednagar, Maharashtra, IndiaPublications
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Research
Two Cases of Autoimmune Haemolytic Anaemia in Patients Infected with HIV
Author(s): Amol Jogdand, Arun Tyagi*, Marcia Waran, AK Srivastava and AB Khare
Patients with HIV/AIDS are prone to develop multiple complications and comorbidities. The hematological complications including cytopenias, lymphoma, multiple myeloma, bone-marrow dysplasia, and coagulation disorders are common. Anemia is the most common cytopenia and develops in almost all patients with HIV/AIDS. Autoimmune Haemolytic Anaemia (AIHA) is a rare cause of anemia in persons infected with HIV. AIHA usually occurs at an advanced stage of HIV disease. The mortality in AIHA is about 11%. RBC autoantibodies are frequently detected after blood transfusion in patients with HIV/AIDS, necessitating screening of patients with anemia for autoantibodies. AIHA may lead to life-threatening thromboembolic complications. Therefore, RBC transfusions should be limited only to cases with severe anemia. Steroids are the first line of treatment. Rituximab, immunosuppressa.. Read More»
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