Hazwani Ahmad Yusof | Malaysia

International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)

Hazwani Ahmad Yusof

Institute of Advanced Medicine and Dentistry, Lifestyle Science Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Kepala Batas, Malaysia


  • Research   
    ACE I/D Gene Polymorphism and Short-Term Endurance Training Response of Untrained Individuals
    Author(s): Hazwani Ahmad Yusof*

    We investigate whether ACE I/D gene polymorphism modulates anthropometric, cardiovascular, biochemical, OGTT, and fat oxidation responses to six weeks of short-term endurance training for untrained adults. Thirty-five untrained healthy individuals initially participated in the pre-test assessment and were screened for ACE I/D genotype. However, only seventeen participants completed three sessions of 45 minutes of endurance training every week for 4 weeks. Using two-way repeated measure ANOVA, the data were clustered among the three classes of ACE I/D genotype groups (II=3, ID=7, DD=7). Six weeks of endurance training resulted in increased the VO2 max (p=0.004), fat oxidation at 40% (p=0.028), 50% (p<0.001), 60% (p=0.011) and 70% (p<0.001) of VO2 max. A significant interaction effect between ACE and endurance training on the fat oxidation variables has been reported (F(18, 12)=2... Read More»

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