Abstract

Study on Clinical and Bacteriological Profile of Acute Tonsillitis

Tonsillitis is a frequent condition noticed in the ENT department of every hospital one out of every 10 children visiting the ENT OPD, suffer from acute tonsillitis. Identification of the organisms responsible and their antibiotic sensitivity pattern can guide in early and timely oral antibiotics and preventing wasting hours of work in hospital stay. This study was done to have an insight into various pathogens that are the cause of acute tonsillitis and evaluating their antibiotic susceptibility. Methods: A descriptive study cross sectional study conducted between January 2018 and January 2019 in a tertiary care center after obtaining ethical approval (Reference number- 222/2018). Patients of age group 5-50 years with acute tonsillitis, who had not taken antibiotics prior to hospital visit, were included. Convenience sampling was done. Collected data were entered in microsoft excel and analyzed using statistical package for social sciences version 24.0. Results: GABHS (50%) was the predominant pathogen followed by Staphylococcus aureus (20.8%). Maximum sensitivity amongst the isolated organism was observed with Linezolid (77.1%) and Vancomycin (72.9%), while maximum resistance was observed for gentamycin (79.2%) ciprofloxacin (62.5%). The maximum isolated organism GABHS was mostly sensitive to frequently used antimicrobials for acute tonsillitis like amoxicillin +clavulanate (75%), ampicillin (79.1%), cefixime (62.5%) and ceftriaxone (70.8%). Conclusion: In this study GABHS was found to be the most common offending pathogen. This study also suggests amoxicillin+clavulanate or ampicillin is still a good choice of initial empirical therapy until the arrival of throat swab culture sensitivity reports.

• PDF