Knowledge management is one of the great achievements of the information and knowledge age. Research shows that the most important factor in the success of knowledge is knowledge-based culture. Therefore, it is necessary to examine the impact of organizational culture on knowledge management; the aim of this study is to examine the impact of organizational culture elements on knowledge management in educational-treatment hospitals in Kerman. This descriptive, cross-sectional and applied study was carried out in 2012 in educational-treatment hospitals of Kerman. Statistical universe included all administrative and Para-clinical staff of educational-treatment hospitals; of them, 258 ones were selected using random cluster sampling method. Data was collected through questionnaires and was analyzed using anova, t-Test ,Pearson correlation and spss statistical software. most studied subjects considered status of organizational culture average (average score: 3.09). The highest score was related to the component “adapt ability culture” with average score of 3.24,and the lowest was related to “collaboration culture” with average score of 2.97. Knowledge management was also in poor condition with average score of 2.76. Finally, a statistically significant relationship was obtained between organizational culture and knowledge management with a correlation coefficient of r=0/56; therefore, as organizational culture increases, knowledge management increases too, and all organizational culture components affect knowledge management. organizational culture was in average condition and knowledge management was in poor condition. Concerning a statistically significant relationship between organizational culture and knowledge management, it can be concluded that it will result in successful changes in hospitals and will help mangers make a systematic prediction of change priorities and codify strategies to perform management techniques and processes successfully.