Background: Rheumatoid arthritis is a chronic, multisystem autoimmune and inflammatory disease, which can result in significant functional disability and depressive symptoms. These changes may have a negative influence on the performance of daily living and work activities, with consequent impact on the quality of life. Aims of study: To assess quality of life in patients with rheumatoid arthritis and finding out the association between sociodemographic variables with physical and mental components of quality of life domains. Methodology: This was a descriptive crosssectional study carried out in rheumatology consultation clinic at Baghdad Teaching Hospital-Medical City during a period from February 01, 2017 to April 01, 2017 on convenient sample of 156 patients with rheumatoid arthritis. Results: The role functioning/physical domain had the highest mean score for quality of life (53.78). Pain domains mean score was the lowest (44.57). There was a significant association between mean quality of life domains and each of educational level, blood pressure state, marital status, monthly income, duration of treatment, source of treatment, and type of treatment. There was a significant association between residence ownership and social functioning domain. Conclusion: The quality of life in rheumatoid arthritis patients was high regarding role limitations due to physical problems, role limitation/emotional and the quality of life was affected by educational level, blood pressure, age group, marital status, residence, monthly income, duration of disease, type of treatment.